UNRIPE FRUIT OF RUBUS FRAXINIFOLIUS AS A POTENTIAL SOURCE OF ANTIOXIDANT AND ANTIELASTASE AGENT

Objective: This research aimed to examine the anti-oxidant activity, antielastase and content of total phenolic flavonoid R. fraxinifolius unripe fruit.
 Methods: The dried fruit was extracted using Soxhlet apparatus with sequence solvent: n-hexane, ethyl acetate, methanol. Each extract determined phenolic, content.
 Result: result showed extracts (n-hexane, methanol) gave IC50>200; 186.84; 19.74 ppm, ability elastase inhibition 6.84+0.9%; 52.23+7.1%; 57.81+5.5% at 100 respectively. methanolic contained 202.2 mg GAE/g 43.89 QE/g extract.
 Conclusion: has shown potential as a DPPH (α, α-diphenyl-β-picrylhydrazyl) radical scavenger anti-elastase. study provides an excellent effect underline importance fruit, it can be developed nutricosmetics, nutraceuticals, or herbal anti-wrinkle cosmetics.